Drug class
SSRIs and SNRIs (antidepressants) and cannabis
There may be additive effects on serotonin signalling, and there are case reports of hypomania or heightened anxiety.
Moderate risk
Why it happens
There may be additive effects on serotonin signalling, and there are case reports of hypomania or heightened anxiety.
What it means for you
For most patients the interaction is mild, if it shows up at all. A small group finds that THC on top of an SSRI makes anxiety worse.
What Tiffany advises
This is reasonable to try once your prescriber knows. Start with a low THC dose and keep a daily mood note so you can spot a change early.
Common examples
Generic names first, then brands.
- sertraline
- fluoxetine
- escitalopram
- venlafaxine
- duloxetine
Body systems involved
- Mood and sleep
Take it further
Check this with my other meds
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